Vitamin C and Niacinamide: Can You Use Them Together?

When it comes to acne treatment, vitamin C and niacinamide are often pitted against each other. Both have anti-inflammatory properties that can be helpful in clearing acne, a common skin condition in which the pores of the skin become clogged. But people may be apprehensive about mixing the two because the combination of vitamin C and niacinamide can lead to the formation of nicotinic acid, a compound that can cause skin irritation and redness. People with sensitive skin may especially experience irritation when using these ingredients together. But there are ways to use vitamin C and niacinamide together without experiencing side effects.

Vitamin C for the skin

Vitamin C, also known as ascorbic acid, is a powerful antioxidant that is essential for various bodily functions. It plays a crucial role in the production of collagen, the protein that helps maintain the structure and elasticity of the skin, says dermatologist Dr. Vijay Singhal.

It is water-soluble, meaning it dissolves in water and the body cannot store it. Therefore, a continuous supply through diet or supplementation is required. It is found naturally in many fruits and vegetables, especially citrus fruits, strawberries, peppers, and leafy greens. In skin care, vitamin C is often used in serums, moisturizers, and other topical products for its many benefits.

Vitamin C offers a variety of benefits to the skin, making it a popular ingredient in skin care products. Here are some of the benefits:

1. It can remove dark spots

Vitamin C may be used in the depigmentation of hyperpigmented spots on the skin, according to research published in the Journal of Oral and Maxillofacial Pathology in 2020. Vitamin C inhibits the production of melanin, which can help lighten hyperpigmentation and remove dark spots, leading to a more even skin tone.

2. Anti-aging

Vitamin C has an anti-aging effect by increasing collagen production, stabilizing collagen fibers, and reducing collagen breakdown, according to research published in the Journal of Clinical and Aesthetic Dermatology in 2017. By promoting collagen production, vitamin C helps reduce the appearance of fine lines and wrinkles, while improving the overall texture and firmness of the skin.

3. Antioxidant protection

As an antioxidant, vitamin C can protect skin from damage caused by free radicals, unstable molecules that can damage skin cells, leading to premature aging and skin cancer, says Dr. Singhal.

4. Get rid of acne scars

Vitamin C has anti-inflammatory and collagen-stimulating properties, according to the National Institutes of Health. So, applying vitamin C products topically can help get rid of acne and improve the appearance of acne scars.

5. Wound healing

Vitamin C can speed up wound healing, says Dr. Singhal. It can also help prevent wound scarring by encouraging the growth of new, healthy skin.

Niacinamide for skin

Niacinamide is a water-soluble vitamin that offers multiple benefits to the skin, says cosmetologist and skin expert Dr. Jatin Mittal. It is found in foods such as meat, fish, milk, eggs, green vegetables, and grains. In skincare, niacinamide is known for its versatility and is used in a variety of products, including serums, creams, and toners.

There are many benefits of niacinamide for the skin. These include:

1. Regulates oil production

In a 2017 study published in Dermatologic Therapy, topical use of nicotinamide was found to significantly reduce acne. Niacinamide also helps balance the skin’s sebum production, making it especially beneficial for those with oily or acne-prone skin.

2. Minimizes the appearance of pores

Because niacinamide helps regulate sebum production, it can also reduce the appearance of large pores, says Dr. Mittal. This, in turn, can make your skin feel much smoother.

3. Reduces inflammation

It has anti-inflammatory properties that can be very helpful in soothing irritated skin. This quality makes it effective in treating conditions such as acne, eczema, and rosacea, says Dr. Singhal.

4. Strengthens the skin barrier

Improves the skin’s natural barrier function, which helps retain moisture and keep out environmental irritants. This can help reduce sensitivity and improve hydration.

5. Improves skin texture

A 2005 study published in the Journal of the American Academy of Dermatology found that applying a skin care product with niacinamide helped improve the appearance of texture, hyperpigmentation, and red spots. Improvements in wrinkles, skin elasticity, and sagging (yellowing of the skin) were also noted during the study.

Is it possible to combine vitamin C and niacinamide?

If you have sensitive skin, you may experience irritation when using these ingredients together, especially if the concentration of vitamin C is high, says Dr. Singhal. In these cases, it may be best to use them at different times of the day or every other day. You can also opt for a lighter vitamin C skin care product with less than 20 percent ascorbic acid.

The combination of niacinamide and vitamin C in skincare is often seen as a power duo. Together, they address a wide range of skin concerns and enhance each other’s benefits:

• Both niacinamide and vitamin C are known for their ability to brighten the skin. When used together, they can significantly improve skin tone, reduce dark spots, and create a radiant complexion.
• While vitamin C stimulates collagen production, niacinamide helps strengthen the skin barrier and reduce fine lines. The combination leads to a firmer, more youthful appearance.
• Vitamin C provides powerful antioxidant protection, while niacinamide has anti-inflammatory properties. Together, they create a robust defense against environmental stressors such as ultraviolet rays and pollution, which can lead to premature aging.
• Niacinamide helps regulate sebum production, thus preventing breakouts, while vitamin C promotes healing and the reduction of post-acne marks.

Using vitamin C and niacinamide together in your skincare routine can maximize their benefits, says Dr. Mittal. Here’s how to use them:

1. Stratification

Apply vitamin C first, followed by niacinamide. Vitamin C serums typically have a lower hydrogen potential or pH, so applying it first allows it to penetrate the skin more effectively. Wait a few minutes after applying vitamin C for it to absorb before applying niacinamide.

2. Morning routine

Vitamin C is best used in the morning for its antioxidant properties, which protect the skin from environmental damage such as UV rays and pollution. After cleansing, apply the vitamin C serum, followed by the niacinamide, then finish with a broad-spectrum sunscreen for added protection.

3. Evening routine

You can use niacinamide at night after cleansing and before moisturizing. This helps strengthen the skin barrier overnight and support skin repair, says Dr. Mittal.

If you’re new to either ingredient, do a patch test to make sure your skin doesn’t react negatively. Additionally, vitamin C can be sensitive to light and air, so store it in a cool, dark place to maintain its potency. Niacinamide, on the other hand, is more stable but should still be stored properly to ensure its longevity.

Are there any side effects if you take niacinamide and vitamin C at the same time?

Niacinamide and vitamin C are generally safe to use together, and side effects are rare. However, there are some potential problems that may arise:

• Some people may experience irritation, redness, or stinging, especially if using a high concentration of vitamin C. If this occurs, consider using a lower concentration or reducing the frequency of application.
• In rare cases, using new products can cause breakouts, especially if you have acne-prone skin. It’s important to introduce these ingredients slowly to monitor your skin’s reaction.
• Caution should be exercised when combining niacinamide and vitamin C with other active ingredients such as retinoids or acids, as this may increase the risk of irritation.

The combination of niacinamide and vitamin C can provide benefits to your skin if used correctly. So, learn how to incorporate these ingredients into your skincare routine if you want to have glowing skin.